Treatment of postherpetic neuralgia: focus on pregabalin

Treatment of postherpetic neuralgia: focus on pregabalin

Postherpetic neuralgia (PHN) is a devastating, chronic pain syndrome that can develop following an outbreak of herpes zoster and becomes increasingly common as patients age. PHN can be difficult to treat and often requires trials of multiple agents to achieve significant pain relief. Pregabalin is the newest agent to gain approval for PHN. Data suggest efficacy for relief of pain and sleep dist...

Treatment of postherpetic neuralgia.

Herpes zoster, a commonly seen condition in daily medical practice, is reported to occur in 10–20% of the population at some time during the lifespan. Chronic, intractable postherpetic neuralgia, a sequela of herpes zoster, presents a clinical challenge. In recent years, effective antiviral agents that can be used in the outpatient setting have been developed for the treatment of herpes zoster ...

Efficacy of pregabalin in the treatment of postherpetic neuralgia: a meta-analysis of randomized controlled trials

We aimed to summarize the efficacy of pregabalin in the treatment of postherpetic neuralgia (PHN) in pain reduction, sleep improvement and overall improvement of the patients in published studies. A literature search for randomized clinical trials (RCTs) investigating the efficacy of pregabalin for PHN was carried out in PubMed, EMBASE and the Cochrane database. For each trial met the inclusion...

Medications in Treatment of Postherpetic Neuralgia

Received December 17, 2013. Accepted December 17, 2013. Correspondence to: Sang Wook Shin Department of Anesthesia and Pain Medicine, Pusan National University School of Medicine, Beomeo-ri, Mulgeum-eup, Yangsan 626-770, Korea Tel: +82-55-360-2752, Fax: +82-55-360-2149, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-...

Evidence-Based Treatment of Postherpetic Neuralgia